Myocarditis: a defect in central immune tolerance?
نویسندگان
چکیده
منابع مشابه
Prevention of autoimmune myocarditis through the induction of antigen-specific peripheral immune tolerance.
BACKGROUND Autoimmunity to cardiac antigens, in particular cardiac myosin, has been observed in humans with myocarditis and in animals with experimental inflammatory heart disease. Current treatments for myocarditis are in many cases immunosuppressive and might lead to increased cardiac damage by reducing host defenses against infectious agents. Therefore, we sought to develop an antigen-specif...
متن کاملkurdish diaspora in central asia and caoucasus
در طول دو قرن گذشته و ظهور روسیه بعنوان قدرتی بزرگ در عرصه جهانی و شروع رقابت با سایر قدرت های بین المللی و منطقهای خصوصا با ایران و عثمانی این ئکشور تلاش کرده است تاد از جمعیت کردها در این کشورها در راستای منافع خود بهره برداری کند در قرون 18 و 19 بارها بخشی از کردها برعلیه امپراطوری عثمانی توسط این کشور مورد استفاده قرار گرفت خصوصا در جنگ های سال 1790تا 1798. این ججنگ ها م.جب شد که بخشی از کر...
15 صفحه اولpolitical economy of china in central asia
this research is about the political economy of china in central asia. in this research the political & economic interactions affected on chinas political economy in central asia are examined. chinas goal of presence in central asia including political-security, economic and energy goals is described in one part. in another part, the trade relations between china and central asian countries ar...
15 صفحه اولDefect Tolerance After the Roadmap
Optical photolithography techniques are approaching physical and economic limits that will drastically reduce the current scaling rate of device miniaturization. New technologies being investigated include Next Generation Lithography (NGL) and Chemically Assembled Electronic Nanotechnology (CAEN), which hold the promise of extremely high densities and sub-10nm feature sizes. However, these tech...
متن کاملSmoldering myocarditis following immune checkpoint blockade
BACKGROUND Severe myocarditis associated with electrical conduction abnormalities and occasionally heart failure has been well documented following treatment with immune checkpoint blockade with an estimated incidence of less than 1%. However, the incidence, early detection, and management of less severe immune-related myocarditis are unknown since most immunotherapy trials have not included ro...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 2011
ISSN: 0021-9738
DOI: 10.1172/jci57211